| Date | Home | Away | Result |
|---|---|---|---|
| 11/7/25 1:30 PM | CD Mirandes | Sporting Gijon | 2-1 |
| 11/8/25 7:00 AM | Real Sociedad B | CD Leganes | 2-1 |
| 11/8/25 9:15 AM | SD Eibar | Albacete Balompie | 3-2 |
| 11/8/25 9:15 AM | SD Huesca | Andorra CF | 2-2 |
| 11/8/25 11:30 AM | Deportivo La Coruna | CyD Leonesa | 3-0 |
| 11/8/25 2:00 PM | FC Malaga | Cordoba CF | 2-2 |
| 11/9/25 7:00 AM | UD Las Palmas | Racing Santander | 3-1 |
| 11/9/25 11:30 AM | FC Granada | Real Saragossa | 3-1 |
| 11/9/25 2:00 PM | FC Cadiz | Real Valladolid | 0-0 |
| 11/10/25 1:30 PM | Burgos CF | CD Castellon | 0-0 |
| 11/26/25 12:00 PM | AD Ceuta FC | UD Almeria | 3-2 |